diff --git a/_locales/en/messages.json b/_locales/en/messages.json
index 59b6436b..f2d2abe8 100644
--- a/_locales/en/messages.json
+++ b/_locales/en/messages.json
@@ -321,6 +321,9 @@
   "excludeStyleByUrlLabel": {
     "message": "Exclude the current URL"
   },
+  "excludeStyleByUrlRedundant": {
+    "message": "The current URL is the domain page"
+  },
   "exportLabel": {
     "message": "Export",
     "description": "Label for the button to export a style ('edit' page) or all styles ('manage' page)"
diff --git a/popup/popup.css b/popup/popup.css
index cb9b123c..bb3d4c49 100644
--- a/popup/popup.css
+++ b/popup/popup.css
@@ -367,6 +367,10 @@ a.configure[target="_blank"] .svg-icon.config {
   display: block;
   margin: 0 auto;
 }
+.entry .menu-item.disabled {
+  opacity: 0.5;
+  background-color: transparent;
+}
 
 /* checkbox */
 .checkbox-container {
diff --git a/popup/popup.js b/popup/popup.js
index 5953143f..64b04f68 100644
--- a/popup/popup.js
+++ b/popup/popup.js
@@ -335,7 +335,16 @@ function createStyleElement(style) {
   entry.classList.toggle('regexp-partial', style.sloppy);
 
   $('.exclude-by-domain-checkbox', entry).checked = styleExcluded(style, 'domain');
-  $('.exclude-by-url-checkbox', entry).checked = styleExcluded(style, 'url');
+
+  const excludeByUrlCheckbox = $('.exclude-by-url-checkbox', entry);
+  const isRedundant = getExcludeRule('domain') === getExcludeRule('url');
+  excludeByUrlCheckbox.checked = !isRedundant && styleExcluded(style, 'url');
+  excludeByUrlCheckbox.disabled = isRedundant;
+
+  const excludeByUrlLabel = $('.exclude-by-url', entry);
+  excludeByUrlLabel.classList.toggle('disabled', isRedundant);
+  excludeByUrlLabel.title = isRedundant ?
+    chrome.i18n.getMessage('excludeStyleByUrlRedundant') : '';
 
   return entry;
 }