diff --git a/background/storage.js b/background/storage.js
index 6e764edd..0fe28c29 100644
--- a/background/storage.js
+++ b/background/storage.js
@@ -129,12 +129,7 @@ function filterStyles({
     exposeIframes: prefs.get('exposeIframes'),
   };
 
-  if (matchUrl && (
-    // Web Store doesn't run content scripts
-    matchUrl.startsWith(URLS.browserWebStore) ||
-    // Chrome 61.0.3161+ doesn't run content scripts on NTP
-    URLS.chromeProtectsNTP && matchUrl.startsWith('chrome://newtab/')
-  )) {
+  if (matchUrl && !URLS.supported(matchUrl)) {
     return asHash ? {} : [];
   }
 
@@ -193,6 +188,7 @@ function filterStylesInternal({
   }
 
   const needSections = asHash || matchUrl !== null;
+  const matchUrlBase = matchUrl && matchUrl.includes('#') && matchUrl.split('#', 1)[0];
 
   let style;
   for (let i = 0; (style = styles[i]); i++) {
@@ -200,7 +196,14 @@ function filterStylesInternal({
     && (url === null || style.url === url)
     && (id === null || style.id === id)) {
       const sections = needSections &&
-        getApplicableSections({style, matchUrl, strictRegexp, stopOnFirst: !asHash});
+        getApplicableSections({
+          style,
+          matchUrl,
+          strictRegexp,
+          stopOnFirst: !asHash,
+          skipUrlCheck: true,
+          matchUrlBase,
+        });
       if (asHash) {
         if (sections.length) {
           filtered[style.id] = sections;
@@ -322,11 +325,20 @@ function deleteStyle({id, notify = true}) {
 }
 
 
-function getApplicableSections({style, matchUrl, strictRegexp = true, stopOnFirst}) {
-  if (!matchUrl.startsWith('http')
-  && !matchUrl.startsWith('ftp')
-  && !matchUrl.startsWith('file')
-  && !matchUrl.startsWith(URLS.ownOrigin)) {
+function getApplicableSections({
+  style,
+  matchUrl,
+  strictRegexp = true,
+  // filterStylesInternal() sets the following to avoid recalc on each style:
+  stopOnFirst,
+  skipUrlCheck,
+  matchUrlBase = matchUrl.includes('#') && matchUrl.split('#', 1)[0],
+  // as per spec the fragment portion is ignored in @-moz-document:
+  // https://www.w3.org/TR/2012/WD-css3-conditional-20120911/#url-of-doc
+  // but the spec is outdated and doesn't account for SPA sites
+  // so we only respect it in case of url("http://exact.url/without/hash")
+}) {
+  if (!skipUrlCheck && !URLS.supported(matchUrl)) {
     return [];
   }
   const sections = [];
@@ -335,7 +347,7 @@ function getApplicableSections({style, matchUrl, strictRegexp = true, stopOnFirs
     const isGlobal = !urls.length && !urlPrefixes.length && !domains.length && !regexps.length;
     const isMatching = !isGlobal && (
       urls.length
-        && urls.indexOf(matchUrl) >= 0
+        && (urls.includes(matchUrl) || matchUrlBase && urls.includes(matchUrlBase))
       || urlPrefixes.length
         && arraySomeIsPrefix(urlPrefixes, matchUrl)
       || domains.length
diff --git a/edit/edit.js b/edit/edit.js
index ff29c0d5..1f64ee57 100644
--- a/edit/edit.js
+++ b/edit/edit.js
@@ -1862,7 +1862,7 @@ function showRegExpTester(event, section = getSectionForChild(this)) {
   });
   queryTabs().then(tabs => {
     const supported = tabs.map(tab => tab.url)
-      .filter(url => URLS.supported.test(url));
+      .filter(url => URLS.supported(url));
     const unique = [...new Set(supported).values()];
     for (const rxData of regexps) {
       const {rx, urls} = rxData;
diff --git a/js/messaging.js b/js/messaging.js
index ffc594bf..7d916bc9 100644
--- a/js/messaging.js
+++ b/js/messaging.js
@@ -31,20 +31,15 @@ const URLS = {
   chromeProtectsNTP:
     parseInt(navigator.userAgent.match(/Chrom\w+\/(?:\d+\.){2}(\d+)|$/)[1]) >= 3161,
 
-  supported: null,
+  supported: url => (
+    url.startsWith('http') && !url.startsWith(URLS.browserWebStore) ||
+    url.startsWith('ftp') ||
+    url.startsWith('file') ||
+    url.startsWith(URLS.ownOrigin) ||
+    !URLS.chromeProtectsNTP && url.startsWith('chrome://newtab/')
+  ),
 };
 
-URLS.supported = new RegExp(
-  '^(file|ftps?|http)://|' +
-  `^https://(?!${
-    URLS.browserWebStore.split('://')[1].replace(/\./g, '\\.')
-  })|` +
-  (URLS.chromeProtectsNTP
-    ? '^chrome://(?!newtab)/|'
-    : '') +
-  '^' + chrome.runtime.getURL('')
-);
-
 let BG = chrome.extension.getBackgroundPage();
 if (BG && !BG.getStyles && BG !== window) {
   // own page like editor/manage is being loaded on browser startup
diff --git a/popup/popup.js b/popup/popup.js
index 09cffa22..364c2b75 100644
--- a/popup/popup.js
+++ b/popup/popup.js
@@ -9,7 +9,7 @@ const ENTRY_ID_PREFIX_RAW = 'style-';
 const ENTRY_ID_PREFIX = '#' + ENTRY_ID_PREFIX_RAW;
 
 getActiveTabRealURL().then(url => {
-  tabURL = URLS.supported.test(url) ? url : '';
+  tabURL = URLS.supported(url) ? url : '';
   Promise.all([
     tabURL && getStylesSafe({matchUrl: tabURL}),
     onDOMready().then(() => {